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Search Results for " non-lysosomal ceramidase "
Targets Recommended: Transferase

1

抑制剂 & 化合物

3

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T40542 Sinbaglustat

ACT-519276,Sinbaglustat,OGT2378

Transferase Metabolism
Sinbaglustat (OGT2378) (OGT2378) 是葡萄糖神经酰胺合成酶 (GCS) 和非溶酶体葡萄糖神经酰胺酶 (GBA2) 的双重抑制剂。Sinbaglustat 是一种可透过血脑屏障的的口服N-烷基亚氨基糖。Sinbaglustat 可用于治疗溶酶体贮积症和研究溶酶体功能障碍相关的中枢神经退行性疾病。

化合物

Sinbaglustat
Cat.No: T40542
Synonym: ACT-519276,Sinbaglustat,OGT2378
Target: Transferase
Cat. No. Product Name Species Expression System
TMPY-00963 ASAH2 Protein, Mouse, Recombinant (His)

N-acylsphingosine amidohydrolase (non-lysosomal...

Mouse HEK293 Cells
ASAH2 (N-acylsphingosine amidohydrolase 2), also known as neutral ceramidase, is a type II integral membrane protein that can be cleaved to produce a soluble secreted protein. The enzyme is abundant in the brush border membranes of the intestine, and also expressed in several tissues such as kidney, brain and liver. The primary structure of ASAH2/neutral ceramidase is highly conserved from bacteria to humans, however, there is a clear difference in the molecular architecture. The murine ASAH2 po...
TMPH-01771 ASAH2 Protein, Human, Recombinant (His)

HNAC1,LCDase (hCD),BCDase,Non-lysosomal

Human E. coli
ASAH2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 25.2 kDa and the accession number is Q9NR71.
TMPH-01985 ASAH2B Protein, Human, Recombinant (His)

ASAH2L,ASAH2B,Putative inactive non-lysosomal

Human E. coli
N/A. ASAH2B Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 23.0 kDa and the accession number is P0C7U1.

重组蛋白

ASAH2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-00963
Species: Mouse
Expression System: HEK293 Cells
ASAH2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01771
Species: Human
Expression System: E. coli
ASAH2B Protein, Human, Recombinant (His)
Cat.No: TMPH-01985
Species: Human
Expression System: E. coli
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